Human CPEB1 activation kit by CRISPRa

CAT#: GA112087

CPEB1 CRISPRa kit - CRISPR gene activation of human cytoplasmic polyadenylation element binding protein 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CPEB1
• Locus ID: 64506
• Kit Components:

  GA112087G1, CPEB1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA112087G2, CPEB1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA112087G3, CPEB1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001079533, NM_001079534, NM_001079535, NM_001288819, NM_001288820, NM_030594, NM_001365240, NM_001365242, NM_001365244, NM_001365247, NM_001365248, NM_001365250, NM_001365241, NM_001365243, NM_001365245, NM_001365246, NM_001365249
• Synonyms: CPE-BP1; CPEB; CPEB-1; h-CPEB; hCPEB-1
• Summary: This gene encodes a member of the cytoplasmic polyadenylation element binding protein family. This highly conserved protein binds to a specific RNA sequence, called the cytoplasmic polyadenylation element, found in the 3' untranslated region of some mRNAs. The encoded protein functions in both the cytoplasm and the nucleus. It is involved in the regulation of mRNA translation, as well as processing of the 3' untranslated region, and may play a role in cell proliferation and tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]