Human LYNX1 activation kit by CRISPRa

CAT#: GA112282

LYNX1 CRISPRa kit - CRISPR gene activation of human Ly6/neurotoxin 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: LYNX1
• Locus ID: 66004
• Kit Components:

  GA112282G1, LYNX1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA112282G2, LYNX1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA112282G3, LYNX1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_177457, NM_177476, NM_177477, NM_001356370
• Synonyms: SLURP2
• Summary: This gene encodes a GPI-anchored, cell membrane bound member of the Ly6/uPAR (LU) superfamily of proteins containing the unique three-finger LU domain. This protein interacts with nicotinic acetylcholine receptors (nAChRs), and is thought to function as a modulator of nAChR activity to prevent excessive excitation. Alternatively spliced transcript variants have been found for this gene. Read-through transcription between this gene and the neighboring downstream gene (SLURP2) generates naturally-occurring transcripts (LYNX1-SLURP2) that encode a fusion protein comprised of sequence sharing identity with each individual gene product. [provided by RefSeq, Sep 2017]