Human GGCT activation kit by CRISPRa

CAT#: GA112312

GGCT CRISPRa kit - CRISPR gene activation of human gamma-glutamylcyclotransferase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GGCT
• Locus ID: 79017
• Kit Components:

  GA112312G1, GGCT gRNA vector 1 in pCas-Guide-CRISPRa

  GA112312G2, GGCT gRNA vector 2 in pCas-Guide-CRISPRa

  GA112312G3, GGCT gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001199815, NM_001199816, NM_001199817, NM_024051, NR_037669
• Synonyms: C7orf24; CRF21; GCTG; GGC
• Summary: The protein encoded by this gene catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides, the penultimate step in glutathione catabolism, and may play a critical role in glutathione homeostasis. The encoded protein may also play a role in cell proliferation, and the expression of this gene is a potential marker for cancer. Pseudogenes of this gene are located on the long arm of chromosome 5 and the short arm of chromosomes 2 and 20. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]