Human AHNAK activation kit by CRISPRa

CAT#: GA112320

AHNAK CRISPRa kit - CRISPR gene activation of human AHNAK nucleoprotein

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: AHNAK
• Locus ID: 79026
• Kit Components:

  GA112320G1, AHNAK gRNA vector 1 in pCas-Guide-CRISPRa

  GA112320G2, AHNAK gRNA vector 2 in pCas-Guide-CRISPRa

  GA112320G3, AHNAK gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001620, NM_024060, NM_001346445, NM_001346446
• Synonyms: AHNAKRS
• Summary: The protein encoded by this gene is a large (700 kDa) structural scaffold protein consisting of a central domain with 128 aa repeats. The encoded protein may play a role in such diverse processes as blood-brain barrier formation, cell structure and migration, cardiac calcium channel regulation, and tumor metastasis. A much shorter variant encoding a 17 kDa isoform exists for this gene, and the shorter isoform initiates a feedback loop that regulates alternative splicing of this gene. [provided by RefSeq, Oct 2016]