Human TSEN34 activation kit by CRISPRa

CAT#: GA112332

TSEN34 CRISPRa kit - CRISPR gene activation of human tRNA splicing endonuclease subunit 34


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USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 3gRNAs, 1 scramble ctrl and 1 enhancer vector
Symbol TSEN34
Locus ID 79042
Kit Components

GA112332G1, TSEN34 gRNA vector 1 in pCas-Guide-CRISPRa

GA112332G2, TSEN34 gRNA vector 2 in pCas-Guide-CRISPRa

GA112332G3, TSEN34 gRNA vector 3 in pCas-Guide-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100058

Disclaimer The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001077446, NM_001282332, NM_001282333, NM_024075
Synonyms LENG5; PCH2C; SEN34; SEN34L
Summary This gene encodes a catalytic subunit of the tRNA splicing endonuclease, which catalyzes the removal of introns from precursor tRNAs. The endonuclease complex is also associated with a pre-mRNA 3-prime end processing factor. A mutation in this gene results in the neurological disorder pontocerebellar hypoplasia type 2. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Oct 2009]

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.