Human WDR77 activation kit by CRISPRa

CAT#: GA112356

WDR77 CRISPRa kit - CRISPR gene activation of human WD repeat domain 77

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: WDR77
• Locus ID: 79084
• Kit Components:

  GA112356G1, WDR77 gRNA vector 1 in pCas-Guide-CRISPRa

  GA112356G2, WDR77 gRNA vector 2 in pCas-Guide-CRISPRa

  GA112356G3, WDR77 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001317062, NM_001317063, NM_001317064, NM_024102, NR_133654
• Synonyms: HKMT1069; MEP-50; MEP50; Nbla10071; p44; p44/Mep50
• Summary: The protein encoded by this gene is an androgen receptor coactivator that forms a complex with protein arginine methyltransferase 5, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins. The encoded protein may be involved in the early stages of prostate cancer, with most of the protein being nuclear-localized in benign cells but cytoplasmic in cancer cells. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]