Human FA2H activation kit by CRISPRa

CAT#: GA112387

FA2H CRISPRa kit - CRISPR gene activation of human fatty acid 2-hydroxylase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: FA2H
• Locus ID: 79152
• Kit Components:

  GA112387G1, FA2H gRNA vector 1 in pCas-Guide-CRISPRa

  GA112387G2, FA2H gRNA vector 2 in pCas-Guide-CRISPRa

  GA112387G3, FA2H gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_024306
• Synonyms: FAAH; FAH1; FAXDC1; SCS7; SPG35
• Summary: This gene encodes a protein that catalyzes the synthesis of 2-hydroxysphingolipids, a subset of sphingolipids that contain 2-hydroxy fatty acids. Sphingolipids play roles in many cellular processes and their structural diversity arises from modification of the hydrophobic ceramide moiety, such as by 2-hydroxylation of the N-acyl chain, and the existence of many different head groups. Mutations in this gene have been associated with leukodystrophy dysmyelinating with spastic paraparesis with or without dystonia. [provided by RefSeq, Mar 2010]