Human Iroquois homeobox protein 3 (IRX3) activation kit by CRISPRa

CAT#: GA112414

IRX3 CRISPRa kit - CRISPR gene activation of human iroquois homeobox 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: IRX3
• Locus ID: 79191
• Kit Components:

  GA112414G1, IRX3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA112414G2, IRX3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA112414G3, IRX3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_024336
• Synonyms: IRX-1; IRXB1
• Summary: IRX3 is a member of the Iroquois homeobox gene family (see IRX1; MIM 606197) and plays a role in an early step of neural development (Bellefroid et al., 1998 [PubMed 9427753]). Members of this family appear to play multiple roles during pattern formation of vertebrate embryos (Lewis et al., 1999 [PubMed 10370142]). [supplied by OMIM, Aug 2009]