Human LRRC2 activation kit by CRISPRa

CAT#: GA112444

LRRC2 CRISPRa kit - CRISPR gene activation of human leucine rich repeat containing 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: LRRC2
• Locus ID: 79442
• Kit Components:

  GA112444G1, LRRC2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA112444G2, LRRC2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA112444G3, LRRC2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_024512, NM_024750
• Synonyms: leucine-rich repeat-containing 2; leucine rich repeat containing 2
• Summary: This gene encodes a member of the leucine-rich repeat-containing family of proteins, which function in diverse biological pathways. This family member may possibly be a nuclear protein. Similarity to the RAS suppressor protein, as well as expression down-regulation observed in tumor cells, suggests that it may function as a tumor suppressor. The gene is located in the chromosome 3 common eliminated region 1 (C3CER1), a 1.4 Mb region that is commonly deleted in diverse tumors. A related pseudogene has been identified on chromosome 2. [provided by RefSeq, Sep 2011]