Human NKAP activation kit by CRISPRa

CAT#: GA112466

NKAP CRISPRa kit - CRISPR gene activation of human NFKB activating protein

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NKAP
• Locus ID: 79576
• Kit Components:

  GA112466G1, NKAP gRNA vector 1 in pCas-Guide-CRISPRa

  GA112466G2, NKAP gRNA vector 2 in pCas-Guide-CRISPRa

  GA112466G3, NKAP gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_024528
• Synonyms: FLJ22626
• Summary: This gene encodes a protein that is involved in the activation of the ubiquitous transcription factor NF-kappaB. This protein is associated with the the histone deacetylase HDAC3 and with the Notch corepressor complex, and it thereby acts as a transcriptional repressor of Notch target genes. It is also required for alphabeta T cell development. A related pseudogene has been identified on chromosome X, while a related and intronless retrocopy, which has an intact CDS and may be functional, is located on chromosome 6. [provided by RefSeq, May 2010]