Human PANK3 activation kit by CRISPRa

CAT#: GA112515

PANK3 CRISPRa kit - CRISPR gene activation of human pantothenate kinase 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PANK3
• Locus ID: 79646
• Kit Components:

  GA112515G1, PANK3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA112515G2, PANK3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA112515G3, PANK3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_024594
• Synonyms: DKFZp686O22247; FLJ12899; MGC16863
• Summary: This gene encodes a protein belonging to the pantothenate kinase family. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by CoA. This family member is expressed most abundantly in the liver. [provided by RefSeq, Jul 2008]