Human PPP1R3B activation kit by CRISPRa

CAT#: GA112527

PPP1R3B CRISPRa kit - CRISPR gene activation of human protein phosphatase 1 regulatory subunit 3B

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PPP1R3B
• Locus ID: 79660
• Kit Components:

  GA112527G1, PPP1R3B gRNA vector 1 in pCas-Guide-CRISPRa

  GA112527G2, PPP1R3B gRNA vector 2 in pCas-Guide-CRISPRa

  GA112527G3, PPP1R3B gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001201329, NM_024607
• Synonyms: GL; PPP1R4; PTG
• Summary: This gene encodes the catalytic subunit of the serine/theonine phosphatase, protein phosphatase-1. The encoded protein is expressed in liver and skeletal muscle tissue and may be involved in regulating glycogen synthesis in these tissues. This gene may be a involved in type 2 diabetes and maturity-onset diabetes of the young. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Jan 2011]