Human CENPU activation kit by CRISPRa

CAT#: GA112545

CENPU CRISPRa kit - CRISPR gene activation of human centromere protein U


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USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 3gRNAs, 1 scramble ctrl and 1 enhancer vector
Symbol CENPU
Locus ID 79682
Kit Components

GA112545G1, CENPU gRNA vector 1 in pCas-Guide-CRISPRa

GA112545G2, CENPU gRNA vector 2 in pCas-Guide-CRISPRa

GA112545G3, CENPU gRNA vector 3 in pCas-Guide-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100058

Disclaimer The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_024629, NR_104593
Synonyms CENP50; CENPU50; KLIP1; MLF1IP; PBIP1
Summary The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA (MIM 117139) replaces histone H3 (see MIM 601128). MLF1IP, or CENPU, is an additional factor required for centromere assembly (Foltz et al., 2006 [PubMed 16622419]). [supplied by OMIM, Mar 2008]

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.