Human CENPU activation kit by CRISPRa
CAT#: GA112545
CENPU CRISPRa kit - CRISPR gene activation of human centromere protein U
Find the corresponding CRISPRi Inhibitor Kit
USD 1,290.00
2 Weeks*
Specifications
Product Data | |
Format | 3gRNAs, 1 scramble ctrl and 1 enhancer vector |
Symbol | CENPU |
Locus ID | 79682 |
Kit Components | GA112545G1, CENPU gRNA vector 1 in pCas-Guide-CRISPRa GA112545G2, CENPU gRNA vector 2 in pCas-Guide-CRISPRa GA112545G3, CENPU gRNA vector 3 in pCas-Guide-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100058 |
Disclaimer | The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_024629, NR_104593 |
Synonyms | CENP50; CENPU50; KLIP1; MLF1IP; PBIP1 |
Summary | The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA (MIM 117139) replaces histone H3 (see MIM 601128). MLF1IP, or CENPU, is an additional factor required for centromere assembly (Foltz et al., 2006 [PubMed 16622419]). [supplied by OMIM, Mar 2008] |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN415240 | CENPU - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
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