Human NARS2 activation kit by CRISPRa

CAT#: GA112585

NARS2 CRISPRa kit - CRISPR gene activation of human asparaginyl-tRNA synthetase 2, mitochondrial

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NARS2
• Locus ID: 79731
• Kit Components:

  GA112585G1, NARS2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA112585G2, NARS2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA112585G3, NARS2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001243251, NM_024678, NR_027479
• Synonyms: asnRS; DFNB94; SLM5
• Summary: This gene encodes a putative member of the class II family of aminoacyl-tRNA synthetases. These enzymes play a critical role in protein biosynthesis by charging tRNAs with their cognate amino acids. This protein is encoded by the nuclear genome but is likely to be imported to the mitochondrion where it is thought to catalyze the ligation of asparagine to tRNA molecules. Mutations in this gene have been associated with combined oxidative phosphorylation deficiency 24 (COXPD24). [provided by RefSeq, Mar 2015]