Human XLF (NHEJ1) activation kit by CRISPRa

CAT#: GA112668

NHEJ1 CRISPRa kit - CRISPR gene activation of human non-homologous end joining factor 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NHEJ1
• Locus ID: 79840
• Kit Components:

  GA112668G1, NHEJ1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA112668G2, NHEJ1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA112668G3, NHEJ1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_024782
• Synonyms: XLF
• Summary: Double-strand breaks in DNA result from genotoxic stresses and are among the most damaging of DNA lesions. This gene encodes a DNA repair factor essential for the nonhomologous end-joining pathway, which preferentially mediates repair of double-stranded breaks. Mutations in this gene cause different kinds of severe combined immunodeficiency disorders. [provided by RefSeq, Jul 2008]