Human TCTN2 activation kit by CRISPRa

CAT#: GA112689

TCTN2 CRISPRa kit - CRISPR gene activation of human tectonic family member 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TCTN2
• Locus ID: 79867
• Kit Components:

  GA112689G1, TCTN2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA112689G2, TCTN2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA112689G3, TCTN2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001143850, NM_024809
• Synonyms: C12orf38; JBTS24; MKS8; TECT2
• Summary: This gene encodes a type I membrane protein that belongs to the tectonic family. Studies in mice suggest that this protein may be involved in hedgehog signaling, and essential for ciliogenesis. Mutations in this gene are associated with Meckel syndrome type 8. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]