Human CBLL1 activation kit by CRISPRa

CAT#: GA112694

CBLL1 CRISPRa kit - CRISPR gene activation of human Cbl proto-oncogene like 1


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USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 3gRNAs, 1 scramble ctrl and 1 enhancer vector
Symbol CBLL1
Locus ID 79872
Kit Components

GA112694G1, CBLL1 gRNA vector 1 in pCas-Guide-CRISPRa

GA112694G2, CBLL1 gRNA vector 2 in pCas-Guide-CRISPRa

GA112694G3, CBLL1 gRNA vector 3 in pCas-Guide-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100058

Disclaimer The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001284291, NM_024814, NR_024199
Synonyms HAKAI; RNF188
Summary This gene encodes an E3 ubiquitin-ligase for the E-cadherin complex and mediates its ubiquitination, endocytosis, and degradation in the lysosomes. The encoded protein contains a RING-finger domain and is also thought to have a role in control of cell proliferation. A related pseudogene has been identified on chromosome X. Alternative splicing results in a non-coding transcript variant. [provided by RefSeq, Aug 2011]

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.