Human CBLL1 activation kit by CRISPRa

CAT#: GA112694

CBLL1 CRISPRa kit - CRISPR gene activation of human Cbl proto-oncogene like 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CBLL1
• Locus ID: 79872
• Kit Components:

  GA112694G1, CBLL1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA112694G2, CBLL1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA112694G3, CBLL1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001284291, NM_024814, NR_024199
• Synonyms: HAKAI; RNF188
• Summary: This gene encodes an E3 ubiquitin-ligase for the E-cadherin complex and mediates its ubiquitination, endocytosis, and degradation in the lysosomes. The encoded protein contains a RING-finger domain and is also thought to have a role in control of cell proliferation. A related pseudogene has been identified on chromosome X. Alternative splicing results in a non-coding transcript variant. [provided by RefSeq, Aug 2011]