Human TRMT2B activation kit by CRISPRa

CAT#: GA112768

TRMT2B CRISPRa kit - CRISPR gene activation of human tRNA methyltransferase 2 homolog B

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TRMT2B
• Locus ID: 79979
• Kit Components:

  GA112768G1, TRMT2B gRNA vector 1 in pCas-Guide-CRISPRa

  GA112768G2, TRMT2B gRNA vector 2 in pCas-Guide-CRISPRa

  GA112768G3, TRMT2B gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001167970, NM_001167971, NM_001167972, NM_024917
• Synonyms: CXorf34; dJ341D10.3
• Summary: This gene encodes a homolog of the TRM2 gene in S. cerevisiae. The yeast gene encodes a tRNA methyltransferase that plays a role in tRNA maturation. The yeast protein also has endo-exonuclease activity and may be involved in DNA double strand break repair. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Nov 2009]