Human UXS 1 (UXS1) activation kit by CRISPRa

CAT#: GA112836

UXS1 CRISPRa kit - CRISPR gene activation of human UDP-glucuronate decarboxylase 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: UXS1
• Locus ID: 80146
• Kit Components:

  GA112836G1, UXS1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA112836G2, UXS1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA112836G3, UXS1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001253875, NM_001253876, NM_025076, NR_045607
• Synonyms: SDR6E1; UGD
• Summary: This gene encodes an enzyme found in the perinuclear Golgi which catalyzes the synthesis of UDP-xylose used in glycosaminoglycan (GAG) synthesis on proteoglycans. The GAG chains are covalently attached to proteoglycans which participate in signaling pathways during development. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2014]