Human PIGZ activation kit by CRISPRa

CAT#: GA112887

PIGZ CRISPRa kit - CRISPR gene activation of human phosphatidylinositol glycan anchor biosynthesis class Z

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PIGZ
• Locus ID: 80235
• Kit Components:

  GA112887G1, PIGZ gRNA vector 1 in pCas-Guide-CRISPRa

  GA112887G2, PIGZ gRNA vector 2 in pCas-Guide-CRISPRa

  GA112887G3, PIGZ gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_025163
• Synonyms: GPI-MT-IV; PIG-Z; SMP3
• Summary: The glycosylphosphatidylinositol (GPI) anchor is a glycolipid found on many blood cells that serves to anchor proteins to the cell surface. This gene encodes a protein that is localized to the endoplasmic reticulum, and is involved in GPI anchor biosynthesis. As shown for the yeast homolog, which is a member of a family of dolichol-phosphate-mannose (Dol-P-Man)-dependent mannosyltransferases, this protein can also add a side-branching fourth mannose to GPI precursors during the assembly of GPI anchors. [provided by RefSeq, Jul 2008]