Human IP3KC (ITPKC) activation kit by CRISPRa

CAT#: GA112899

ITPKC CRISPRa kit - CRISPR gene activation of human inositol-trisphosphate 3-kinase C

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ITPKC
• Locus ID: 80271
• Kit Components:

  GA112899G1, ITPKC gRNA vector 1 in pCas-Guide-CRISPRa

  GA112899G2, ITPKC gRNA vector 2 in pCas-Guide-CRISPRa

  GA112899G3, ITPKC gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_025194
• Synonyms: IP3-3KC; IP3KC
• Summary: This gene encodes a member of the inositol 1,4,5-trisphosphate [Ins(1,4,5)P(3)] 3-kinase family of enzymes that catalyze the phosphorylation of inositol 1,4,5-trisphosphate to 1,3,4,5-tetrakisphosphate. The encoded protein is localized to the nucleus and cytoplasm and has both nuclear import and nuclear export activity. Single nucleotide polymorphisms in this gene are associated with Kawasaki disease. [provided by RefSeq, Sep 2009]