Human SCDGFB (PDGFD) activation kit by CRISPRa

CAT#: GA112911

PDGFD CRISPRa kit - CRISPR gene activation of human platelet derived growth factor D

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PDGFD
• Locus ID: 80310
• Kit Components:

  GA112911G1, PDGFD gRNA vector 1 in pCas-Guide-CRISPRa

  GA112911G2, PDGFD gRNA vector 2 in pCas-Guide-CRISPRa

  GA112911G3, PDGFD gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_025208, NM_033135
• Synonyms: IEGF; MSTP036; SCDGF-B; SCDGFB
• Summary: The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a core motif of eight cysteines, seven of which are found in this factor. This gene product only forms homodimers and, therefore, does not dimerize with the other three family members. It differs from alpha and beta members of this family in having an unusual N-terminal domain, the CUB domain. Two splice variants have been identified for this gene. [provided by RefSeq, Jul 2008]