Human CSP (DNAJC5) activation kit by CRISPRa

CAT#: GA112929

DNAJC5 CRISPRa kit - CRISPR gene activation of human DnaJ heat shock protein family (Hsp40) member C5

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: DNAJC5
• Locus ID: 80331
• Kit Components:

  GA112929G1, DNAJC5 gRNA vector 1 in pCas-Guide-CRISPRa

  GA112929G2, DNAJC5 gRNA vector 2 in pCas-Guide-CRISPRa

  GA112929G3, DNAJC5 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_025219
• Synonyms: CLN4; CLN4B; CSP; DNAJC5A; mir-941-2; mir-941-3; mir-941-4; mir-941-5; NCL
• Summary: This gene is a member of the J protein family. J proteins function in many cellular processes by regulating the ATPase activity of 70 kDa heat shock proteins. The encoded protein plays a role in membrane trafficking and protein folding, and has been shown to have anti-neurodegenerative properties. The encoded protein is known to play a role in cystic fibrosis and Huntington's disease. A pseudogene of this gene is located on the short arm of chromosome 8. [provided by RefSeq, Nov 2010]