Human ADAM33 activation kit by CRISPRa

CAT#: GA112930

ADAM33 CRISPRa kit - CRISPR gene activation of human ADAM metallopeptidase domain 33

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ADAM33
• Locus ID: 80332
• Kit Components:

  GA112930G1, ADAM33 gRNA vector 1 in pCas-Guide-CRISPRa

  GA112930G2, ADAM33 gRNA vector 2 in pCas-Guide-CRISPRa

  GA112930G3, ADAM33 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001282447, NM_025220, NM_153202
• Synonyms: C20orf153; DJ964F7.1
• Summary: This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This protein is a type I transmembrane protein implicated in asthma and bronchial hyperresponsiveness. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2013]