Human LY6G5C activation kit by CRISPRa

CAT#: GA112964

LY6G5C CRISPRa kit - CRISPR gene activation of human lymphocyte antigen 6 family member G5C

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: LY6G5C
• Locus ID: 80741
• Kit Components:

  GA112964G1, LY6G5C gRNA vector 1 in pCas-Guide-CRISPRa

  GA112964G2, LY6G5C gRNA vector 2 in pCas-Guide-CRISPRa

  GA112964G3, LY6G5C gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001002848, NM_001002849, NM_025262
• Synonyms: C6orf20; G5c; G5c, NG33, C6orf20, LY6G5CA, LY6G5CB; LY6G5CA; LY6G5CB; lymphocyte antigen-6 G5C; lymphocyte antigen 6 complex, locus G5C; lymphocyte antigen 6 complex G5C; NG33
• Summary: LY6G5C belongs to a cluster of leukocyte antigen-6 (LY6) genes located in the major histocompatibility complex (MHC) class III region on chromosome 6. Members of the LY6 superfamily typically contain 70 to 80 amino acids, including 8 to 10 cysteines. Most LY6 proteins are attached to the cell surface by a glycosylphosphatidylinositol (GPI) anchor that is directly involved in signal transduction (Mallya et al., 2002 [PubMed 12079290]). [supplied by OMIM, Mar 2008]