Human TAS1R1 activation kit by CRISPRa

CAT#: GA112999

TAS1R1 CRISPRa kit - CRISPR gene activation of human taste 1 receptor member 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TAS1R1
• Locus ID: 80835
• Kit Components:

  GA112999G1, TAS1R1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA112999G2, TAS1R1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA112999G3, TAS1R1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_138697, NM_177539, NM_177540, NM_177541
• Synonyms: GM148; GPR70; T1R1; TR1
• Summary: The protein encoded by this gene is a G protein-coupled receptor and is a component of the heterodimeric amino acid taste receptor T1R1+3. The T1R1+3 receptor responds to L-amino acids but not to D-enantiomers or other compounds. Most amino acids that are perceived as sweet activate T1R1+3, and this activation is strictly dependent on an intact T1R1+3 heterodimer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]