Human KCNH6 activation kit by CRISPRa

CAT#: GA113015

KCNH6 CRISPRa kit - CRISPR gene activation of human potassium voltage-gated channel subfamily H member 6

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: KCNH6
• Locus ID: 81033
• Kit Components:

  GA113015G1, KCNH6 gRNA vector 1 in pCas-Guide-CRISPRa

  GA113015G2, KCNH6 gRNA vector 2 in pCas-Guide-CRISPRa

  GA113015G3, KCNH6 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001278919, NM_001278920, NM_030779, NM_173092
• Synonyms: ERG-2; ERG2; hERG-2; HERG2; Kv11.2
• Summary: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Jul 2013]