Human SLC38A1 activation kit by CRISPRa

CAT#: GA113052

SLC38A1 CRISPRa kit - CRISPR gene activation of human solute carrier family 38 member 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SLC38A1
• Locus ID: 81539
• Kit Components:

  GA113052G1, SLC38A1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA113052G2, SLC38A1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA113052G3, SLC38A1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001077484, NM_001278387, NM_001278388, NM_001278389, NM_001278390, NM_030674
• Synonyms: ATA1; NAT2; SAT1; SNAT1
• Summary: Amino acid transporters play essential roles in the uptake of nutrients, production of energy, chemical metabolism, detoxification, and neurotransmitter cycling. SLC38A1 is an important transporter of glutamine, an intermediate in the detoxification of ammonia and the production of urea. Glutamine serves as a precursor for the synaptic transmitter, glutamate (Gu et al., 2001 [PubMed 11325958]). [supplied by OMIM, Mar 2008]