Human PLA2G12A activation kit by CRISPRa

CAT#: GA113080

PLA2G12A CRISPRa kit - CRISPR gene activation of human phospholipase A2 group XIIA


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USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 3gRNAs, 1 scramble ctrl and 1 enhancer vector
Symbol PLA2G12A
Locus ID 81579
Kit Components

GA113080G1, PLA2G12A gRNA vector 1 in pCas-Guide-CRISPRa

GA113080G2, PLA2G12A gRNA vector 2 in pCas-Guide-CRISPRa

GA113080G3, PLA2G12A gRNA vector 3 in pCas-Guide-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100058

Disclaimer The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_030821
Synonyms GXII; PLA2G12; ROSSY
Summary Secreted phospholipase A2 (sPLA2) enzymes liberate arachidonic acid from phospholipids for production of eicosanoids and exert a variety of physiologic and pathologic effects. Group XII sPLA2s, such as PLA2G12A, have relatively low specific activity and are structurally and functionally distinct from other sPLA2s (Gelb et al., 2000 [PubMed 11031251]). [supplied by OMIM, Mar 2008]

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.