Human GERP (TRIM8) activation kit by CRISPRa

CAT#: GA113082

TRIM8 CRISPRa kit - CRISPR gene activation of human tripartite motif containing 8

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TRIM8
• Locus ID: 81603
• Kit Components:

  GA113082G1, TRIM8 gRNA vector 1 in pCas-Guide-CRISPRa

  GA113082G2, TRIM8 gRNA vector 2 in pCas-Guide-CRISPRa

  GA113082G3, TRIM8 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_030912, NM_001345950, NR_144321
• Synonyms: GERP; RNF27
• Summary: This gene encodes a member of the tripartite motif (TRIM) protein family. Based on similarities to other proteins, the encoded protein is suspected to be an E3 ubiquitin-protein ligase. Regulation of this gene may be altered in some cancers. Mutations resulting in a truncated protein product have been observed in early-onset epileptic encephalopathy (EOEE). [provided by RefSeq, Sep 2016]