Human SNX27 activation kit by CRISPRa

CAT#: GA113087

SNX27 CRISPRa kit - CRISPR gene activation of human sorting nexin 27

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SNX27
• Locus ID: 81609
• Kit Components:

  GA113087G1, SNX27 gRNA vector 1 in pCas-Guide-CRISPRa

  GA113087G2, SNX27 gRNA vector 2 in pCas-Guide-CRISPRa

  GA113087G3, SNX27 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001330723, NM_030918
• Synonyms: MRT1; MY014
• Summary: This gene encodes a member of the sorting nexin family, a diverse group of cytoplasmic and membrane-associated proteins involved in endocytosis of plasma membrane receptors and protein trafficking through these compartments. All members of this protein family contain a phosphoinositide binding domain (PX domain). A highly similar protein in mouse is responsible for the specific recruitment of an isoform of serotonin 5-hydroxytryptamine 4 receptor into early endosomes, suggesting the analogous role for the human protein. [provided by RefSeq, Jul 2008]