Human DIAPH3 activation kit by CRISPRa

CAT#: GA113100

DIAPH3 CRISPRa kit - CRISPR gene activation of human diaphanous related formin 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: DIAPH3
• Locus ID: 81624
• Kit Components:

  GA113100G1, DIAPH3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA113100G2, DIAPH3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA113100G3, DIAPH3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001042517, NM_001258366, NM_001258367, NM_001258368, NM_001258369, NM_001258370, NM_030932
• Synonyms: AN; AUNA1; DIA2; diap3; DRF3; mDia2; NSDAN
• Summary: This gene encodes a member of the diaphanous subfamily of the formin family. Members of this family are involved in actin remodeling and regulate cell movement and adhesion. Mutations in this gene are associated with autosomal dominant auditory neuropathy 1. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]