Human PPP1R14C activation kit by CRISPRa

CAT#: GA113115

PPP1R14C CRISPRa kit - CRISPR gene activation of human protein phosphatase 1 regulatory inhibitor subunit 14C

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PPP1R14C
• Locus ID: 81706
• Kit Components:

  GA113115G1, PPP1R14C gRNA vector 1 in pCas-Guide-CRISPRa

  GA113115G2, PPP1R14C gRNA vector 2 in pCas-Guide-CRISPRa

  GA113115G3, PPP1R14C gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_030949
• Synonyms: CPI17-like; KEPI; NY-BR-81
• Summary: The degree of protein phosphorylation is regulated by a balance of protein kinase and phosphatase activities. Protein phosphatase-1 (PP1; see MIM 176875) is a signal-transducing phosphatase that influences neuronal activity, protein synthesis, metabolism, muscle contraction, and cell division. PPP1R14C is an inhibitor of PP1 (Liu et al., 2002 [PubMed 11812771]). [supplied by OMIM, Feb 2010]