Human FCRL4 activation kit by CRISPRa

CAT#: GA113163

FCRL4 CRISPRa kit - CRISPR gene activation of human Fc receptor like 4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: FCRL4
• Locus ID: 83417
• Kit Components:

  GA113163G1, FCRL4 gRNA vector 1 in pCas-Guide-CRISPRa

  GA113163G2, FCRL4 gRNA vector 2 in pCas-Guide-CRISPRa

  GA113163G3, FCRL4 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_031282
• Synonyms: CD307d; FCRH4; IGFP2; IRTA1
• Summary: This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein has four extracellular C2-type immunoglobulin domains, a transmembrane domain and a cytoplasmic domain that contains three immune-receptor tyrosine-based inhibitory motifs. This protein may play a role in the function of memory B-cells in the epithelia. Aberrations in the chromosomal region encoding this gene are associated with non-Hodgkin lymphoma and multiple myeloma. [provided by RefSeq, Apr 2009]