Human TCF7L1 activation kit by CRISPRa

CAT#: GA113164

TCF7L1 CRISPRa kit - CRISPR gene activation of human transcription factor 7 like 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TCF7L1
• Locus ID: 83439
• Kit Components:

  GA113164G1, TCF7L1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA113164G2, TCF7L1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA113164G3, TCF7L1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_031283
• Synonyms: TCF-3; TCF3
• Summary: This gene encodes a member of the T cell factor/lymphoid enhancer factor family of transcription factors. These transcription factors are activated by beta catenin, mediate the Wnt signaling pathway and are antagonized by the transforming growth factor beta signaling pathway. The encoded protein contains a high mobility group-box DNA binding domain and participates in the regulation of cell cycle genes and cellular senescence. [provided by RefSeq, Nov 2010]