Human UCK (UCK1) activation kit by CRISPRa

CAT#: GA113199

UCK1 CRISPRa kit - CRISPR gene activation of human uridine-cytidine kinase 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: UCK1
• Locus ID: 83549
• Kit Components:

  GA113199G1, UCK1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA113199G2, UCK1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA113199G3, UCK1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001135954, NM_001261450, NM_001261451, NM_001318519, NM_031432, NR_134666, NR_134667
• Synonyms: URK1
• Summary: This gene encodes a uridine-cytidine kinase that catalyzes the phosphorylation of uridine and cytidine to uridine monophosphate (UMP) and cytidine monophosphate (CMP) but not the phosphorylation of deoxyribonucleosides or purine ribonucleosides. This enzyme can also phosphorylate uridine and cytidine analogs and uses both ATP and GTP as a phosphate donor. Alternative splicing results in multiple splice variants encoding distinct isoforms. [provided by RefSeq, May 2012]