Human NUDT12 activation kit by CRISPRa

CAT#: GA113207

NUDT12 CRISPRa kit - CRISPR gene activation of human nudix hydrolase 12

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: NUDT12
• Locus ID: 83594
• Kit Components:

  GA113207G1, NUDT12 gRNA vector 1 in pCas-Guide-CRISPRa

  GA113207G2, NUDT12 gRNA vector 2 in pCas-Guide-CRISPRa

  GA113207G3, NUDT12 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001300741, NM_031438
• Summary: Nucleotides are involved in numerous biochemical reactions and pathways within the cell as substrates, cofactors, and effectors. Nudix hydrolases, such as NUDT12, regulate the concentrations of individual nucleotides and of nucleotide ratios in response to changing circumstances (Abdelraheim et al., 2003 [PubMed 12790796]). [supplied by OMIM, Mar 2008]