Human URP2 (FERMT3) activation kit by CRISPRa

CAT#: GA113243

FERMT3 CRISPRa kit - CRISPR gene activation of human fermitin family member 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: FERMT3
• Locus ID: 83706
• Kit Components:

  GA113243G1, FERMT3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA113243G2, FERMT3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA113243G3, FERMT3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_031471, NM_178443
• Synonyms: KIND3; MIG-2; MIG2B; UNC112C; URP2; URP2SF
• Summary: Kindlins are a small family of proteins that mediate protein-protein interactions involved in integrin activation and thereby have a role in cell adhesion, migration, differentiation, and proliferation. The protein encoded by this gene has a key role in the regulation of hemostasis and thrombosis. This protein may also help maintain the membrane skeleton of erythrocytes. Mutations in this gene cause the autosomal recessive leukocyte adhesion deficiency syndrome-III (LAD-III). Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jan 2010]