Human HMCN1 activation kit by CRISPRa

CAT#: GA113284

HMCN1 CRISPRa kit - CRISPR gene activation of human hemicentin 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: HMCN1
• Locus ID: 83872
• Kit Components:

  GA113284G1, HMCN1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA113284G2, HMCN1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA113284G3, HMCN1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_031935
• Synonyms: ARMD1; FBLN6; FIBL-6; FIBL6
• Summary: This gene encodes a large extracellular member of the immunoglobulin superfamily. A similar protein in C. elegans forms long, fine tracks at specific extracellular sites that are involved in many processes such as stabilization of the germline syncytium, anchorage of mechanosensory neurons to the epidermis, and organization of hemidesmosomes in the epidermis. Mutations in this gene may be associated with age-related macular degeneration. [provided by RefSeq, Jul 2008]