Human HDAC10 activation kit by CRISPRa

CAT#: GA113315

HDAC10 CRISPRa kit - CRISPR gene activation of human histone deacetylase 10

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: HDAC10
• Locus ID: 83933
• Kit Components:

  GA113315G1, HDAC10 gRNA vector 1 in pCas-Guide-CRISPRa

  GA113315G2, HDAC10 gRNA vector 2 in pCas-Guide-CRISPRa

  GA113315G3, HDAC10 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001159286, NM_032019
• Synonyms: HD10
• Summary: The protein encoded by this gene belongs to the histone deacetylase family, members of which deacetylate lysine residues on the N-terminal part of the core histones. Histone deacetylation modulates chromatin structure, and plays an important role in transcriptional regulation, cell cycle progression, and developmental events. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]