Human CCDC8 activation kit by CRISPRa

CAT#: GA113329

CCDC8 CRISPRa kit - CRISPR gene activation of human coiled-coil domain containing 8

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CCDC8
• Locus ID: 83987
• Kit Components:

  GA113329G1, CCDC8 gRNA vector 1 in pCas-Guide-CRISPRa

  GA113329G2, CCDC8 gRNA vector 2 in pCas-Guide-CRISPRa

  GA113329G3, CCDC8 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_032040
• Synonyms: 3M3; p90; PPP1R20
• Summary: This gene encodes a coiled-coil domain-containing protein. The encoded protein functions as a cofactor required for p53-mediated apoptosis following DNA damage, and may also play a role in growth through interactions with the cytoskeletal adaptor protein obscurin-like 1. Mutations in this gene are a cause of 3M syndrome-3 (3M3). [provided by RefSeq, Dec 2011]