Human KBTBD7 activation kit by CRISPRa

CAT#: GA113362

KBTBD7 CRISPRa kit - CRISPR gene activation of human kelch repeat and BTB domain containing 7

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: KBTBD7
• Locus ID: 84078
• Kit Components:

  GA113362G1, KBTBD7 gRNA vector 1 in pCas-Guide-CRISPRa

  GA113362G2, KBTBD7 gRNA vector 2 in pCas-Guide-CRISPRa

  GA113362G3, KBTBD7 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_032138
• Synonyms: DKFZp434E2318
• Summary: The protein encoded by this gene is a transcriptional activator, having been shown to increase the transcription of activator protein-1 and serum response element. The encoded protein can also form a complex with KBTBD6 and CUL3, which regulates the ubiquitylation and degradation of TIAM1, which is a regulator of RAC1. [provided by RefSeq, Jul 2016]