Human ZIC4 activation kit by CRISPRa

CAT#: GA113375

ZIC4 CRISPRa kit - CRISPR gene activation of human Zic family member 4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ZIC4
• Locus ID: 84107
• Kit Components:

  GA113375G1, ZIC4 gRNA vector 1 in pCas-Guide-CRISPRa

  GA113375G2, ZIC4 gRNA vector 2 in pCas-Guide-CRISPRa

  GA113375G3, ZIC4 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001168378, NM_001168379, NM_001243256, NM_032153, NR_033118, NR_033119, NR_040762
• Synonyms: FLJ42609; FLJ45833
• Summary: This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. Members of this family are important during development, and have been associated with X-linked visceral heterotaxy and holoprosencephaly type 5. This gene is closely linked to the gene encoding zinc finger protein of the cerebellum 1, a related family member on chromosome 3. Heterozygous deletion of these linked genes is involved in Dandy-Walker malformation, which is a congenital cerebellar malformation. Multiple transcript variants have been identified for this gene. [provided by RefSeq, Dec 2009]