Human ATRIP activation kit by CRISPRa

CAT#: GA113380

ATRIP CRISPRa kit - CRISPR gene activation of human ATR interacting protein

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ATRIP
• Locus ID: 84126
• Kit Components:

  GA113380G1, ATRIP gRNA vector 1 in pCas-Guide-CRISPRa

  GA113380G2, ATRIP gRNA vector 2 in pCas-Guide-CRISPRa

  GA113380G3, ATRIP gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001271022, NM_001271023, NM_032166, NM_130384
• Summary: This gene encodes an essential component of the DNA damage checkpoint. The encoded protein binds to single-stranded DNA coated with replication protein A. The protein also interacts with the ataxia telangiectasia and Rad3 related protein kinase, resulting in its accumulation at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2012]