Human CCDC98 (FAM175A) activation kit by CRISPRa

CAT#: GA113391

ABRAXAS1 CRISPRa kit - CRISPR gene activation of human abraxas 1, BRCA1 A complex subunit

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ABRAXAS1
• Locus ID: 84142
• Kit Components:

  GA113391G1, ABRAXAS1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA113391G2, ABRAXAS1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA113391G3, ABRAXAS1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001345962, NM_139076
• Synonyms: ABRA1; CCDC98
• Summary: This gene encodes a protein that binds to the C-terminal repeats of breast cancer 1 (BRCA1) through a phospho-SXXF motif. The encoded protein recruits ubiquitin interaction motif containing 1 protein to BRCA1 protein and is required for DNA damage resistance, DNA repair, and cell cycle checkpoint control. Pseudogenes of this gene are found on chromosomes 3 and 8. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]