Human DARPP32 (PPP1R1B) activation kit by CRISPRa

CAT#: GA113395

PPP1R1B CRISPRa kit - CRISPR gene activation of human protein phosphatase 1 regulatory inhibitor subunit 1B

SDS

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Find the corresponding CRISPRi Inhibitor Kit

USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 3gRNAs, 1 scramble ctrl and 1 enhancer vector
Symbol PPP1R1B
Locus ID 84152
Kit Components

GA113395G1, PPP1R1B gRNA vector 1 in pCas-Guide-CRISPRa

GA113395G2, PPP1R1B gRNA vector 2 in pCas-Guide-CRISPRa

GA113395G3, PPP1R1B gRNA vector 3 in pCas-Guide-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100058
Disclaimer The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001242464, NM_032192, NM_181505
Synonyms DARPP-32; DARPP32
Summary This gene encodes a bifunctional signal transduction molecule. Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor. As a target for dopamine, this gene may serve as a therapeutic target for neurologic and psychiatric disorders. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

Other Versions

SKU Description Size Price
KN400916 PPP1R1B - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.
    • 1 kit

USD 1,290.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.