Human ARID5B activation kit by CRISPRa

CAT#: GA113398

ARID5B CRISPRa kit - CRISPR gene activation of human AT-rich interaction domain 5B

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ARID5B
• Locus ID: 84159
• Kit Components:

  GA113398G1, ARID5B gRNA vector 1 in pCas-Guide-CRISPRa

  GA113398G2, ARID5B gRNA vector 2 in pCas-Guide-CRISPRa

  GA113398G3, ARID5B gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001244638, NM_032199
• Synonyms: DESRT; MRF-2; MRF2
• Summary: This gene encodes a member of the AT-rich interaction domain (ARID) family of DNA binding proteins. The encoded protein forms a histone H3K9Me2 demethylase complex with PHD finger protein 2 and regulates the transcription of target genes involved in adipogenesis and liver development. This gene also plays a role in cell growth and differentiation of B-lymphocyte progenitors, and single nucleotide polymorphisms in this gene are associated with acute lymphoblastic leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]