Human RBED1 (ELMOD3) activation kit by CRISPRa

CAT#: GA113407

ELMOD3 CRISPRa kit - CRISPR gene activation of human ELMO domain containing 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ELMOD3
• Locus ID: 84173
• Kit Components:

  GA113407G1, ELMOD3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA113407G2, ELMOD3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA113407G3, ELMOD3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001135021, NM_001135022, NM_001135023, NM_001329791, NM_001329792, NM_001329793, NM_032213, NR_138131, NR_138132, NR_138133
• Synonyms: DFNB88; LST3; RBED1; RBM29
• Summary: This gene encodes a member of the engulfment and cell motility family of GTPase-activating proteins that regulate Arf GTPase proteins. Members of this family are defined by a conserved engulfment and cell motility domain. In rat cochlea, the encoded protein is found in stereocilia, kinocilia and cuticular plate of developing hair cells suggesting a function for this protein in cochlear sensory cells. An allelic variant of this family has been associated with autosomal recessive nonsyndromic deafness-88 in humans. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2016]