Human SGIP1 activation kit by CRISPRa

CAT#: GA113450

SGIP1 CRISPRa kit - CRISPR gene activation of human SH3 domain GRB2 like endophilin interacting protein 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SGIP1
• Locus ID: 84251
• Kit Components:

  GA113450G1, SGIP1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA113450G2, SGIP1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA113450G3, SGIP1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001308203, NM_032291, NM_001350217, NM_001350218
• Summary: SGIP1 functions as an endocytic protein that affects signaling by receptors in neuronal systems involved in energy homeostasis via its interaction with endophilins (see SH3GL3; MIM 603362) (Trevaskis et al., 2005 [PubMed 15919751] and Uezu et al., 2007 [PubMed 17626015]). [supplied by OMIM, Mar 2008]