Human TMEM107 activation kit by CRISPRa

CAT#: GA113508

TMEM107 CRISPRa kit - CRISPR gene activation of human transmembrane protein 107

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TMEM107
• Locus ID: 84314
• Kit Components:

  GA113508G1, TMEM107 gRNA vector 1 in pCas-Guide-CRISPRa

  GA113508G2, TMEM107 gRNA vector 2 in pCas-Guide-CRISPRa

  GA113508G3, TMEM107 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_032354, NM_183065, NM_001351278, NM_001351279, NM_001351280, NR_147092
• Synonyms: GRVS638; PRO1268
• Summary: This gene encodes a transmembrane protein and component of the primary cilia transition zone. The encoded protein regulates ciliogenesis and ciliary protein composition. Human fibroblasts expressing a mutant allele of this gene exhibit reduced numbers of cilia, altered cilia length, and impaired sonic hedgehog signaling. In human patients, different mutations in this gene cause different ciliopathies, including Meckel-Gruber syndrome and orofaciodigital syndrome. [provided by RefSeq, May 2017]